[] Two randomized controlled trials during pregnancy involving pregnant women less than 16 weeks of gestation showed that 4,000 IU vitamin D/day was superior to 400 or 2,000 IU/day by the second trimester in reaching adequate levels of at least 40 ng/mL (100 nmol/L) of 25(OH) D
This is unknown, but ~12-24 hours may often be reasonable
Upon binding and activating the receptor, tirzepatide may subsequently exert greater therapeutic effects by regulating adipose tissue metabolism, energy expenditure, and potentially central appetite regulation
Most patients on a properly structured 36 month protocol notice meaningful changes in body composition, not just the scale
The cheapest option is generic Saxenda (liraglutide), which costs less than $500 with a free SingleCare discount card
These seemingly random bits are incompressible 38,39,40 , reducing the efficiency of compression algorithms