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Not one was a true biological non-responder
Transgenic lines expressing roGFP2 indicated a change in the glutathione redox potential upon AITC treatment The application of AITC led to stronger responses for the glutathione mutants than for WT, which may suggest an essential role for this tripeptide in the AITC-induced physiological responses
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Studies for which no response was received were excluded
Lessons from clinical trials demonstrate these effects are mainly driven by reductions in albuminuria
Given the typical timeline for FDA approval, the medication may not be on the market until 2027
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