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Expansion of tumor-associated Treg cells upon disruption of a CTLA-4-dependent feedback loop
Singh, C
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Cancer epidemiology, biomarkers & prevention : a publication of theAmerican Association for Cancer Research, cosponsored by the AmericanSociety of Preventive Oncology
Tumor-associated macrophages (TAMs), the primary pro-inflammatory cells within tumors, exhibit increased secretion of IL-1 in response to moderate hypoxia
This has potential relevance for circulatory conditions, but human data is limited
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