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CstB Product Analysis The product analysis was performed similarly to the oxygen-consumption assay, except that the reaction was carried out in approximately 80% 18 O-labeled water and without using an oxygraph

SARS-CoV-2 spike protein S1 induces fibrin(ogen) resistant to fibrinolysis: implications for microclot formation in COVID-19

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The approval was based on data from the ongoing Phase II PHAROS clinical trial, which is studying the combination in both treatment-nave and previously treated patients with BRAF V600E-mutant metastatic NSCLC