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All of these findings are in rodents, and their relevance to humans is unestablished

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There was an error in the number of syringes and it was corrected immediately

Mice tolerated the treatment well throughout the study period

Inhibiting the enzyme therefore has consequences on two fronts at once: it spares S-adenosylmethionine, and it leaves nicotinamide available to other routes, including the salvage pathway that supplies NAD