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They mimic naturally occurring gastrointestinal hormones such as glucagon-like peptide (GLP-1) and gastric inhibitory peptide (GIP) that suppress appetite after eating and stimulate the release of insulin from the pancreas
If a rash appears, think of two buckets
For persons with sufficient ASCVD risk and type 2 diabetes, GLP-1 RAs and SGLT2 inhibitors can, and often should, be used in combination
For this reason, researchers are exploring potential behavioral effects of GLP-1 medications, even though this is not their intended or approved use
Heart rate increase: about 5-10 bpm above baseline, peaking near week 24, then declining
Singh has received research grant support from Mayo Clinic, the National Network of Depression Centers (NNDC), and Breakthrough Discoveries for Thriving with Bipolar Disorder (BD2)
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