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2016 Jan;48(1):41-51
Its primary mechanism of action is the upregulation of brain-derived neurotrophic factor (BDNF), a protein that supports neuronal survival, synaptic plasticity, and the formation of new neural connections
longum with the synbiotics FOS, GOS, and inulin decreased depression and raised blood levels of a brain-derived neurotrophic factor in depressed patients compared to controls (251)
Thats why incorporating foods that are rich in glutathione is a smart, natural way to support optimal health
Notably, the PERK-ATF4 arm of the UPR can be activated as an adaptive response to negatively regulate ferroptosis and promote survival
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