This is likely because GLP-1 agonists can delay the emptying of bile from the gallbladder
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The primary one is competition from other GLP-1 drugs, especially from Eli Lillys Mounjaro (tirzepatide), which has shown greater efficacy in weight loss and diabetes control
All GLP-1 receptor agonists are safe in terms of cardiovascular outcomes, and liraglutide, semaglutide, albiglutide, dulaglutide and efpeglenatide have been shown to have cardiovascular benefits in cardiovascular outcomes trials [22]
Certain peptides are optimally dosed spread throughout the day to simulate physiologic pulses
Typically, treatment for type 2 diabetes involves lifestyle changes, eating a healthy diet, and taking medication