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PEA is known for its neuroprotective, anti-inflammatory, and analgesic properties, interacting with multiple receptors including CB1, CB2, PPAR, and COX2. Sodium Bicarbonate buffers stomach acidity, maximizing peptide absorption even if capsules dissolve prematurely

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Oral doses tend to be higher - 500 mcg to 1000 mcg twice daily - because oral bioavailability is presumably lower than injectable, though we don't have good human pharmacokinetic data

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What makes GHK-Cu particularly remarkable is the breadth of its influence