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The apolipoprotein E 4 (APOE4) allele confers the highest risk for AD, whereas APOE2 acts protectively

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All experiments were performed following the ARRIVE guidelines ( to report animal experiments

The three disulfide bridges of the IGF-I core are retained, which is why the molecular formula carries nine sulfur atoms, six from cysteine and three from methionine

Ferroptosis is a type of autophagy-dependent cell death

Another recent study related to glutamine metabolism using NMR revealed a link between the human oncoprotein NSD3s and the rewiring of cancer metabolism by taking the glutaminolysis pathway (Fig