However, as Exercise NZ notes: while fat loss is indeed happening, for many users this comes at the cost of lean muscle mass loss of muscle that underpins strength, metabolism, immune function and long-term resilience
Results will depend on: How consistently the medication is taken How quickly the dose is increased Daily habits such as food choices, movement, sleep, and alcohol intake Individual differences in metabolism and hormone response Because GLP-1 helps people eat less with less effort, many describe weight loss on these medications as finally doable compared to every diet they tried before
Excess free iron (Fe2+) generates reactive oxygen species (ROS) through the Fenton reaction, causing lipid peroxidation of the membrane (144)
Current Alternatives While waiting for Retatrutide approval, Canadian patients with prescriptions can access: Wegovy (semaglutide): Health Canada approved, available through pharmacies Saxenda (liraglutide): Health Canada approved, daily injection option Zepbound (tirzepatide) is FDA approved but Health Canada approval status should be verified with current regulatory updates
You may be considered if: Your medical history supports participation in a supervised weight management program Your body mass index or weight-related health factors indicate additional support may be helpful You are looking for structured medical oversight rather than a self-directed approach You are willing to participate in ongoing monitoring and follow-up This program is not suitable for everyone
Its safe and effective for most people, but consult your healthcare provider before starting any new supplement