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Drugs that trigger insulin release after meals, called DPP-4 inhibitors (DPP-4is), were found to be the least effective among the four at maintaining glucose levels, without offering any unique benefits

Synergistic activity of the MCL-1 inhibitor S63845 with midostaurin in preclinical human models of FLT3-ITD mutated acute myeloid leukemia (AML)

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Contraindications include personal or family history of medullary thyroid carcinoma, multiple endocrine neoplasia type 2, uncontrolled hypertension, and certain kidney conditions