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The human data is almost nonexistent

Effect of dapagliflozin on the rate of decline in kidney function in patients with chronic kidney disease with and without type 2 diabetes: A prespecified analysis from the DAPA-CKD trial

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This approach helps patients get the most benefits while avoiding unwanted side effects

However, it can lead to a change in your intestinal microbiota and change how your body processes certain foods or medications, like Ozempic