Understanding the cellular and molecular mechanisms of BBB dysfunction in brain disorders is crucial for elucidating the sustenance of neural computations under pathological conditions and for developing treatments for these diseases
Discussed above
Aberrant oligodendroglialvascular interactions disrupt the bloodbrain barrier, triggering CNS inflammation
23 Factors such as convenience (e.g., frequency of administration) and tolerability are certainly important, but the choice of agent may also be determined by the individualized glycemic needs of the patient
The main cardiovascular outcomes were major adverse cardiovascular events, defined as nonfatal myocardial infarction, nonfatal stroke, or cardiovascular death, and hospitalization for heart failure or cardiovascular death
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