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Most patients report mild to moderate fatigue during the first month
It is doable but requires attention
In the self-controlled case series design, use of GLP-1 RAs was associated with a lower incidence rate ratio (IRR) of suicide or suicide attempts one year after treatment initiation (IRR: 0.45
After four weeks, your doctor will likely want to increase your dose
Glycemic mechanism and insulin sparing sensitization not secretion: fasting insulin and C-peptide fall while insulin sensitivity (HOMA2-%S) rises +31.8/+43.2/+49.9% (SURPASS J-mono, Hamamoto 2025)
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