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A case-control study (Urbanski et al

33 One small study suggests that glutathione supplementation, along with conventional treatments, may help aid in treating eczema by reducing oxidative stress

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Among them, the glutamate produced by the decomposition of glutamine via GLS not only provides the raw material for the synthesis of GSH but is also further metabolized into -ketoglutarate (-KG) in the mitochondria under the action of glutamate dehydrogenase (GLUD1) or transaminases and then enters the tricarboxylic acid cycle to produce ATP [29]

The tissue retains more regenerative capacity when damage is relatively fresh