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Blood 98:103a, 2001

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The TXN system is crucial for normal cellular function as TXN knockout mice were reported to be embryonic lethal [27]

Researchers demonstrated that nuclear HDAC1-3, in association with SIRT (dual classified into class III HDACs), exhibited vibrant activities towards delactylases in vitro and inhibited Kla of both H3K18 and H4K5, among which HDAC3 predominates as the leading eraser in a zinc-dependent manner [83]

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