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This is considered to be the reason why these patients do not respond to pharmacological treatments 5

Sutton MA, Schmidt EF, Choi KH, Schad CA, Whisler K, Simmons D et al (2003)

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The cells were collected after treatment, washed twice with cold phosphate-buffered saline, and treated with 1 mL of cold citrate buffer (0.24 M sucrose, 40 mM sodium citrate, pH 7.6)

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MR imaging of acute cervical spinal ligamentous and soft tissue trauma