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These medications are not FDA-approved for safety or effectiveness but may be used when alternatives are not available or appropriate
PEG can increase the apparent relative molecular mass of spherically modified proteins by 5 to 10 times and significantly reduce the glomerular filtration of protein drugs
Theranostics 11 , 22472262 (2021)
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A variety of antioxidant supplements, including vitamins C, glutathione, selenium, and zinc, have been shown to improve sperm quality by reducing ROS levels and preventing oxidative damage (104, 105)
The resulting diminishment of Hes1 expression and other Notch effectors compromises the sphere-forming ability of CSCs and their capacity to maintain the undifferentiated state (72, 73)
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