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Why won't it fail
Compared with SLE, RA, IBD, and MS, direct mechanistic evidence for amino acid metabolism-mediated macrophage polarization remains relatively limited in other autoimmune diseases
Liraglutide is a weaker alternative by the numbers, but it remains FDA-approved for weight management and has the longest real-world safety track record of any GLP-1 for obesity
10.1210/jc.2014-3865 13
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