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Our goal was to elucidate the complex relationship between GLP-1 receptor agonists and bone health, particularly in the context of orthopedic surgery, to inform clinical practice and identify areas for future research

The active compound is tirzepatide, a synthetic peptide that acts as a dual agonist at both the glucose-dependent insulinotropic polypeptide receptor (GIPR) and the glucagon-like peptide-1 receptor (GLP-1R)

Incidence, prevalence, and co-occurrence of autoimmune disorders over time and by age, sex, and socioeconomic status: a population-based cohort study of 22 million individuals in the UK

Because deep sleep is one of the most restorative phases of our sleep architecture, DSIP is of interest for those seeking to improve sleep quality, recovery, and even manage stress-induced interruptions in sleep patterns, promoting stress reduction

Dense GLP-1R immunostaining, mostly consisting of perikarya and dendrites, was observed in the sacral dorsal commissural nucleus (Fig