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Individuals with medical conditions, pregnant or breastfeeding women should consult with a healthcare practitioner before using this supplement
Metabolism 27 , 201208
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People use it to promote healing and reduce inflammation, especially in muscles and the digestive system
The pharmacokinetic investigation determined that this compound is being hydrolyzed by the microbial colonies and metabolized in the mucosa of the intestine through phase II enzymes, submitted to methylation and conjugation process, forming methylated, glucuronic, and sulphated conjugates by the action of o-methyltransferase, UDP-glucosyltransferases, and sulfotransferases, respectively (Monteiro Espindola et al., 2019)
Chronic structural damage like advanced arthritis, complete tears, bone spurs, and disc herniations typically show minimal response
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