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they are not instructions for self-preparation

However, supplementing excessively high levels of B12 can have some adverse effects

Although doctors may recommend B12 injection for this purpose when weakness is related to peripheral neuropathy, more research is needed on effectiveness, and Medicare doesnt consider this medically necessary

Different Forms of Vitamin B12 It might surprise you to learn that not all vitamin B12 is created equal

It plays a vital role in brain function and the production of DNA and red blood cells

A 2019 randomized controlled trial of lipotropic injections (methionine, inositol, choline, B12) versus saline placebo in 120 participants on ad libitum diets found 0.8 kg (1.76 pounds) difference at 12 weeks, not statistically significant (p=0.18) (Karbalay-Doust et al., Journal of Research in Medical Sciences , 2019)