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[2] [3] [11] Tissue deficiencies may negatively affect nerve cells, bone marrow, and the skin

Additional research and clinical trials are needed to validate this therapeutic strategy in humans, which could initiate T21 prenatal therapy

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S2CID 19077356

Circulation 107:13591365 Yasumura EG, Stilhano RS, Samoto VY, Matsumoto PK, de Carvalho LP, Valero Lapchik VB, Han SW (2012) Treatment of mouse limb ischemia with an integrative hypoxia-responsive vector expressing the vascular endothelial growth factor gene

Results were expressed as percent variations