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Numerous practice guidelines recommend multicomponent, evidence-based nutritional and behavioral therapy for adults with obesity, but use of such treatments with GLP-1s is not widespread [73]
40 KimuraR.OkouchiM.FujiokaH.IchiyanagiA.RyugeF.MizunoT.et al (2009)
Also, fixed-ratio combination has the advantage of a less complex treatment regimen, with only one injection a day
Cox proportional hazards models were used to evaluate the association between GLP-1 RA use and osteoporosis risk, adjusting for age, sex, BMI, blood pressure, lipid profile, renal function, osteocalcin, vitamin D levels, HbA1c, statin use, antihypertensive medication use, and smoking status
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