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Phiel CJ, Zhang F, Huang EY et al (2001) Histone Deacetylase Is a Direct Target of Valproic Acid, a Potent Anticonvulsant, Mood Stabilizer, and Teratogen

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They should also not be used in children younger than 6 months

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As(III) simply stunts the root elongation, but Cd(II) treatment leads to wavy root growth in the WT