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Seiler A, Schneider M, Forster H, Roth S, Wirth EK, Culmsee C et al

In contrast, a PUFA-enriched Western diet evoked patchy small intestinal inflammation in Gpx4 +/IEC mice, while the colon was unaffected

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Since NNMT is expressed in adipose, hepatic, and gut tissues 50,51,52 , and these tissues heavily cross-talk with the gut microbiome 53,54,55 , NNMTi treatment or its resulting weight loss effects 8,9 may modulate the microbiome

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For example, while other growth factors might cause cloudy vision by growing vessels where they don't belong, research shows BPC-157 can promote healing in the eye while actively maintaining corneal transparency by opposing pathological vessel growth