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The STEP UP trial in people with obesity tested the higher dose of semaglutide (7.2mg) against the 2.4mg dose and placebo over 72 weeks in over 1,400 adults living with obesity without type 2 diabetes

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doi:10.1038/laban0512-129 pmid:22517091 Bondolfi L, Ermini F, Long JM, Ingram DK, Jucker M (2004) Impact of age and caloric restriction on neurogenesis in the dentate gyrus of C57BL/6 mice

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For managing Type 2 diabetes, Ozempic shows significant reductions in A1c, but both medications may be effective at promoting weight loss

Environmental Factors: Pollution: Exposure to environmental pollutants and toxins can damage the skin and contribute to pigmentation problems