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10m-sections were cut on a cryostat (Leica Biosystems) and collected on SuperFrost Plus slides, then air-dried at room temperature for 1 h followed by incubation at 40 C for 5 min

Both substantially outperform currently available medications

Pawlak and others reviewed studies of B12 deficiency among vegetarians and vegans using serum B12 (Pawlak, 2014) as well as methylmalonic acid and holotranscobalamin (Pawlak, 2013)

Half of those tested as part of the 36mg group achieved body weight reduction of more than 10%, compared to the 7% of participants achieving the same threshold for the placebo group

This establishes a reference point for monitoring throughout treatment