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163 CYP450 enzymes in the liver regulate the metabolism of many anticancer drugs (e.g., imatinib and erlotinib), and altered activity can lead to reduced efficacy or increased toxicity
As an important regulator in cancer metabolism, dysregulated GGCT expression has been confirmed to be closely associated with the progression of multiple malignancies [3,4,5,6,7,8,9,10]
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Watson, PatelVB (Academic, San Diego, 2011), pp
According to one study, Glutathione helps reduce oxidative stress by either stimulating or reducing the bodys immunological response
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