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These patients are taking medications during critical periods of development and growth, says Dan Cooper, MD, a pediatrician and obesity researcher at the University of California, Irvine

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Preclinical and clinical evidence supports these effects in the cardiovascular system, liver, kidneys, and joints

Acknowledgements The authors are thankful to the University of Agriculture, Faisalabad, Pakistan, and Neurobiology Research Group, Department of Cellular Biology, Genetics, Histology and Pharmacology, Faculty of Medicine, University of Valladolid (Spain) for their collaboration for their support