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Seek immediate medical attention if you experience: Severe, persistent abdominal pain that radiates to the back Abdominal pain that does not improve and is accompanied by nausea and vomiting Pain that worsens after eating, particularly fatty foods Fever combined with severe abdominal tenderness If pancreatitis is suspected, semaglutide should be discontinued immediately and not restarted

GLP-1 Guide Frequently Asked Questions Semaglutide targets one hormone to help reduce appetite, while Tirzepatide targets two for enhanced fullness and support

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avg body weight lost with Semaglutide (NEJM STEP 1 trial, 68 weeks) 2025% avg body weight lost with Tirzepatide (SURMOUNT-1, 7288 weeks) of semaglutide patients lost 5% of body weight (STEP 1 trial)of semaglutide patients lost 5% of body weight (STEP 1 trial) Week 14: Appetite reduction, smaller portions naturally Month 13: Steady fat loss begins, 12 lbs/week avg Month 36: Visible body composition change, reduced visceral fat 68 weeks: Average 14.9% total body weight reduction Ozempic for weight loss and Wegovy for weight loss produce comparable outcomes at equivalent doses