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The widely repeated claim that Dihexa is "seven orders of magnitude more potent than BDNF" originates from that flagged McCoy paper and reflects an assay-specific in-vitro spine-density measurement picomolar Dihexa versus nanomolar BDNF in one assay not a millions-fold advantage in a living brain

Contaminants including residual solvents, heavy metals, and bacterial endotoxins require testing beyond simple purity assessment

Treatments like finasteride work by blocking the enzyme that converts testosterone to DHT

And the effect of stress on our cells is oxidative stress

LPS-free indicates that the peptide has been tested to confirm the absence of lipopolysaccharides, which can interfere with experimental outcomes

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