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At the same time, a 2025 systematic review and meta-analysis found that GLP-1 receptor agonists actually increased total testosterone, luteinizing hormone, and follicle-stimulating hormone levels in men with overweight or obesity
The upside is that the long-term energy benefits may be even more impactful for this group
Feb 14 2023;20(4)doi:10.3390/ijerph20043337 Anto L, Blesso CN
Orforglipron is a non-peptide
Wegovy, an injectable form of semaglutide for the treatment of obesity, was approved in 2021
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