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Presented for research literature review only Summer KH et al

Erickson, J

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In addition, treatment did not restore neurotrophin signaling and was associated with reductions in BDNF and NGF levels, suggesting a limited and potentially unfavorable impact on pathways involved in synaptic plasticity and neurodevelopment

(4) increased hepatic and renal urea cycle intermediates suggesting hypercatabolism and upregulation of the urea cycle independent of impaired renal clearance of nitrogenous waste

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