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Beyond migration, actin dynamics regulate the morphological changes required for endothelial cells to form tube-like structures during angiogenesis, the contractile ring formation required for cell division in proliferating repair cell populations, the stress fibre organisation that determines fibroblast mechanical properties in wound contraction, and the signalling scaffolding roles of the actin cytoskeleton in multiple growth factor receptor pathways
Whether it produces meaningfully better outcomes than once-daily dosing in humans remains unknown
Y., Lin, Y., Ko, Y
These precautions may seem excessive for subcutaneous injections, but consistency with good practices eliminates preventable complications
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