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Cautious use of parenteral cyanocobalamin is also recommended in patients with renal impairment, including premature neonates, because of the possibility of greater aluminum accumulation, which may cause central nervous system and bone toxicity

Alternative volumes for different resulting concentrations Rule: For AOD-9604 we recommend 2 ml as the optimal compromise volume

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By sticking to these tips and making treatment fit each persons needs, we can help them get the best results from B12 therapy

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Figure 2: Changes in the histolopathological scores amongst the four experimental treatment groups