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This study also investigated the expression of DPP-4 and found it to be present on the vascular endothelium, including the local capillaries in the lamina propria adjacent to the GLP-1 producing L-cells, thus providing an explanation for the rapid degradation of the peptide once it had been released

In HT, apoptosis plays a central role in follicular cell destruction and peripheral deletion of autoreactive lymphocytes

10.1007/s10658-015-0621-z 164 VenisseJ

One meta-analysis reported a statistically significant increase in risk, whereas the remaining seven showed no significant associations

And patients taking dual-agonists also showed bigger improvements in metabolic markers, blood pressure, triglycerides, and blood sugar control, beyond just the scale