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Two 2013 systematic reviews of interventions concluded that the modest benefit of propionyl-L-carnitine on walking performance was equivalent or superior to that obtained with drugs approved for claudication in the US (e.g., pentoxyphylline, cilostazol) yet inferior to improvements seen with supervised exercise interventions (69, 70)

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The Integrative Psychopharmacology Framework This brings me to a broader point about how I think about prescribing as a psychiatrist

"It is up to you to make the lifestyle changes for long-term results." McConnell advised other GLP-1 patients to have a plan for how to maintain their healthy lifestyles, including eating well and getting exercise, once theyve stopped taking these medications

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