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While vitamin B12 naturally occurs in the body, making allergic reactions to it exceedingly rare, certain additives or preservatives in some preparations could cause mild localized reactions, such as redness or itching
Walsh et al
Medline Plus, National Library of Medicine
Presented for research literature review only deSmidt PC et al
Evaluate your risk tolerance for research compounds versus FDA-approved medications
However, sometimes a person may experience allergic reactions or sensitivity (Ensure to contact your doctor about any potential complications.) Medicare Part D prescription drug plans expressly exclude coverage for vitamins - although some Medicare plans do cover "excluded" drugs such as B-12 vitamin injections as "Bonus" or Supplemental drugs
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