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2015;11(10):e1004477
GLP-1s work by mimicking a natural hormone called GLP-1 (glucagon-like peptide-1), which is released in the gut after eating
Expected Timelines 4-8 Weeks Subtle changes in skin texture and firmness 8-12 Weeks Visible improvements in wrinkles and skin quality 12+ Weeks Optimal results with continued use Clinical evidence includes 12-week studies showing improved skin laxity, clarity, and reduced wrinkles, outperforming vitamin C and retinoic acid in comparative trials with 70% increase in skin elasticity after 12 weeks
Seeruttun, S
As for the weight loss that often occurs when taking these medications, its also typically greater on Mounjaro about 14.7% with Mounjaro versus 5% with Trulicity per the recent phase 3 trial but this is highly dependent on an individuals ability to tolerate the medications side effects as they ramp up their dosage, as well as the lifestyle changes they also make
Continue taking your semaglutide as prescribed unless your healthcare provider advises otherwise, and focus on maintaining hydration and nutritional intake despite reduced appetite
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