However, the complexity of peptide synthesis means that demonstrating equivalence is closer to the biosimilar process than to typical small-molecule generics
This is particularly important for medications with narrow therapeutic windows, including thyroid hormones, blood thinners, and certain cardiac medications
The findings were published in JAMA Internal Medicine on January 20, showing that glucagon-like peptide-1 (GLP-1) receptor agonists like Ozempic carry an 8.2% higher risk of chronic kidney disease than sodium-glucose cotransporter-2 (SGLT2) inhibitors
At the same time, GLP-1s are being adopted across a healthcare system thats fragmented and under pressure to keep pace
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Studies have revealed its potential to reduce markers of inflammation, such as C-reactive protein (CRP), which are associated with an increased risk of cardiovascular disease