YZC has been shown to improve metabolic function, reshape and regulate gut microbiota, reduce TMAO synthesis, and inhibit NLRP3 inflammasome activation, thereby ameliorating LPS-induced lung inflammation and injury in septic ALI mice
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The SPE column (Supelco/Sigma-Aldrich, Bellefonte, PA) was activated with 2 mL methanol first and balanced with 2 mL deionized water
Expression of Ets-1
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AMPK suppresses NF-B expression, which lowers the inflammatory response by upregulating SIRT1 expression (Chen et al., 2016)