GLP-1 medications (glucagon-like peptide-1 receptor agonists) are used mainly for weight management and type 2 diabetes
One limitation of most PK and PD studies is the enrollment of healthy subjects, whereas the major target population for use of GLP1RAs are patients with diabetes and obesity who may have co-morbidities that might affect the PK results
doi:10.1001/jama.2013.284427 Jones DW et al (2025): 2025 AHA/ACC/AANP/AAPA/ABC/ACCP/ACPM/AGS/AMA/ASPC/NMA/PCNA/SGIM Guideline for the Prevention, Detection, Evaluation and Management of High Blood Pressure in Adults
I mean, that is our career calling and it makes me so frustrated, angry and sad when women who decide that they do need to go on these medications are accused of being lazy and not doing the basics
Anti-IGF therapies showed potent anticancer effects and the ability to suppress cancer resistance to various chemotherapy drugs in in vivo and in vitro preclinical studies
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