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The scenario depicted, clearly indicates that GSH is a weighty protagonist of the huge network governing the decision between life and death, through the modulation of cellular redox state

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Concurrently, DON impaired transmembrane transport and lipid homeostasis by suppressing genes such as ATP-binding cassette subfamily A member 4 (ABCA4) 73 , whereas GA induced transporters for detoxification and lipid efflux (e.g., ABCB11 74 and ABCA1 75 )

( a ) Flow cytometry analysis of HT1080 and ( b ) NIH3T3 cells simultaneously treated with RSL3 (1.13 M) and 17-estradiol (10 M) for indicated time points

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