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Five participants withdrew from the trial, including four in the placebo arm (two participants did not provide a reason for withdrawal, one participant did not have a weight loss response, and the remaining participant withdrew due to adverse event (AE) reasons)

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Based on the aforementioned effects and mechanisms of 5-ASA, we employed 5-ASA as the positive control drug in our in vivo experiments

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Step 6: Inject your dose Insert the needle into the skin