Older GLP-1 receptor agonists like liraglutide (Victoza, Saxenda) showed somewhat larger heart rate increases in trial data compared to semaglutide
En personas con sobrepeso y obesidad sin diabetes, tirzepatida mostr una reduccin de peso media de hasta el 22,55 (23,6 kg) en la semana 72 y 4 de cada 10 pacientes consiguieron una prdida de peso igual o superior al 25%
24.2% at 48 weeks in Phase 2 Tirzepatide : Up to 20.9% body weight reduction (SURMOUNT trials) Advantage : Retatrutide Regulatory Status# Retatrutide : Phase 1-3 clinical trials
Some patients prefer other options when ibuprofen causes stomach sensitivity or dryness
Side Effects and Risks Both types can cause stomach issues like nausea, vomiting, diarrhea, or constipation
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