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Two studies from Denmark [32, 36], using a grace period of 90 days (as was done in our main analyses), reported that approximately 20% of both GLP-1 receptor agonist users [32, 36] and SGLT2 inhibitor users [32] had discontinued treatment within 1 year of treatment initiation

GLP-1s in Midlife the Hormone Therapy Connection Animal research suggests that GLP-1 hormones have different effects in males and females, with females being more sensitive to GLP-1 receptor activation

Hampl SE, Hassink SG, Skinner AC, et al

It's the chronic, 24/7 elevation of GH (as seen in certain medical conditions or with improper use of exogenous GH) that poses a much more formidable threat to long-term metabolic health

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Adherence to these standards ensures efficacy and consistent safety