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Chen R, Ovbiagele B, Feng W (2016) Diabetes and stroke: epidemiology, pathophysiology, pharmaceuticals and outcomes

Consistent with the incretin-mediated delivery of the PPAR// agonist, the metabolic effects of GLP-1GIPLani were blunted in DIO mice with pharmacological or genetic inhibition of GLP-1R, GIPR or PPAR, and vanished in double-incretin receptor knockout (DIR-KO) mice

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Khatri N, Sumadhura B, Kumar S, Kaundal RK, Sharma S, Datusalia AK

Ensuring equitable access to these effective but high-cost medications, as well as supporting individuals so that they can stay on the therapy long-term, should be a priority for our clinicians and policymakers. Semaglutide, which is approved for managing diabetes, obesity and preventing recurrent cardiovascular events, is already the nations top-selling drug by pharmaceutical spending