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Remember that women experience GI side effects at 2.5 times the rate of men on equivalent doses
Whereas folate is important to initiate the methylation cycle, B12 is required for the activation of folate from dietary folate to 5-methyltetrahydrofolate, so that it can go on to create the methyl groups SAMe and methionine
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Their basal metabolic rate has dropped
People with a BMI of 30 or above can lose an average of 14.9% of their weight in 68 weeks
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